Schematic model of the signaling pathway involved in ACSL4-induced up-regulation of intramitochondrial AA, LOX products, COX-2 and PGE2 production in the development of an aggressive phenotype in breast cancer cells.
Oleanolic acid inhibits cervical cancer Hela cell proliferation thro
ACSL4 | SpringerLink
Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells - ScienceDirect
Biology | Free Full-Text | The ACSL4 Network Regulates Cell Death and Autophagy in Diseases
JCI - RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis
ACSL4 Antibody (A-5) | SCBT - Santa Cruz Biotechnology
ACSL4 Antibody (F-4) | SCBT - Santa Cruz Biotechnology
Activation of ALOX12 by a multi-organelle-orienting photosensitizer drives ACSL4-independent cell ferroptosis | Cell Death & Disease
The positive feedback between ACSL4 expression and O-GlcNAcylation contributes to the growth and survival of hepatocellular carcinoma | Aging
Cancers | Free Full-Text | ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
IJMS | Free Full-Text | ACSL4-Mediated Ferroptosis and Its Potential Role in Central Nervous System Diseases and Injuries
Schematic model of the signaling pathway involved in ACSL4-induced... | Download Scientific Diagram
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. - Abstract - Europe PMC
ACSL4: Biomarker, mediator and target in quad | EurekAlert!
Frontiers | Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis
PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis | Nature Cell Biology
Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells | PLOS ONE
Fatty acid activation in carcinogenesis and cancer development: Essential roles of long‑chain acyl‑CoA synthetases (Review)
Seco-Lupane Triterpene Derivatives Induce Ferroptosis through GPX4/ACSL4 Axis and Target Cyclin D1 to Block the Cell Cycle | Journal of Medicinal Chemistry
Acyl-CoA synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression - ScienceDirect